SCHEMBL2867417

SCHEMBL2867417

CC([C]C(C)c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.44
CYP2D6 P10635 2/20 0.44
ADRA2C P18825 2/20 0.44
TSHR P16473 2/20 0.44
CHRM2 P08172 1/20 0.44
ADRA1A P35348 1/20 0.44
RGS12 O14924 1/20 0.44
GLA P06280 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
NFKB1 P19838 1/20 0.44
HTR2A P28223 1/20 0.44
CYP2C19 P33261 1/20 0.44
THPO P40225 1/20 0.44
GNAI1 P63096 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TAAR1 Q96RJ0 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9303811 0.82 MIF (0.44) MIFCYP2D6ADRA2CTSHRTAAR1
SCHEMBL144604 0.81 MIF (0.40) MIFCYP2D6ADRA2CTSHRHTR2A
SCHEMBL8733281 0.80 MIF (0.43) MIFCYP2D6ADRA2CTSHRTAAR1
SCHEMBL8711629 0.78 MIF (0.41) MIFCYP2D6ADRA2CTAAR1ADRA2A
SCHEMBL198507 0.78 TSHR (0.52) MIFCYP2D6ADRA2CTSHRHSD17B10
SCHEMBL7494289 0.78 MIF (0.52) MIFCYP2D6ADRA2CTSHRTAAR1
SCHEMBL28208618 0.78 TSHR (0.52) MIFCYP2D6ADRA2CTSHRHSD17B10
SCHEMBL97552 0.78 MIF (0.41) MIFCYP2D6ADRA2CTAAR1ADRA2A
SCHEMBL7039581 0.78 TSHR (0.52) MIFCYP2D6ADRA2CTSHRHSD17B10
SCHEMBL3151083 0.78 MIF (0.41) MIFCYP2D6ADRA2CTAAR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632505-B1 ETHYLENE POLYMER MITSUI CHEMICALS INC (JP) 2016-09-07 EP disclosed
EP-2511305-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-10-17 EP disclosed
EP-2465879-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
EP-2465878-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
US-7795194-B2 Synthetic lubricating oil and lubricating oil composition MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
US-7452946-B2 copolymer with C3 to C10 alpha -olefin; provides a blow-molded product and an extrusion-molded product excellent in moldability, mechanical strength and outward appearance; produced in the presence of a solid catalyst MITSUI CHEMICALS, INC. (JP) 2008-11-18 US disclosed
US-20060199925-A1 Ethylene polymer MITSUI CHEMICALS, INC. (JP) 2006-09-07 US disclosed
US-20060116303-A1 decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability MITSUI CHEMICALS, INC. (JP) 2006-06-01 US disclosed
EP-1632505-A1 ETHYLENE POLYMER Mitsui Chemicals, Inc. (JP) 2006-03-08 EP disclosed
EP-1548018-A1 CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME Mitsui Chemicals, Inc. (JP) 2005-06-29 EP disclosed