Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968801 | 1.00 | MAPT (0.60) | MAPTALDH1A1HCAR2FAAHCYP3A4 | |
| SCHEMBL10027878 | 0.89 | MAPT (0.58) | MAPTALDH1A1HCAR2FAAHCYP3A4 | |
| SCHEMBL10027885 | 0.89 | MAPT (0.58) | MAPTALDH1A1HCAR2FAAHCYP3A4 | |
| SCHEMBL16852835 | 0.86 | MAPT (0.58) | MAPTALDH1A1HCAR2CYP3A4TSHR | |
| SCHEMBL7148317 | 0.84 | HCAR2 (0.54) | MAPTHCAR2FAAH | |
| SCHEMBL30563965 | 0.84 | HCAR2 (0.54) | MAPTHCAR2FAAH | |
| SCHEMBL10027889 | 0.83 | MAPT (0.55) | MAPTALDH1A1HCAR2FAAHCYP3A4 | |
| SCHEMBL1468542 | 0.82 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHALOX15 | |
| SCHEMBL11795363 | 0.82 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHALOX15 | |
| SCHEMBL873713 | 0.82 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527420-A | Antibacterial calcium-dependent antibiotic (CDA) analogs and methods of treating bacterial infections | 香港大学 | 2021-10-22 | — | — | CN | disclosed |