Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778541 | 0.94 | MAPT (0.58) | MAPTALDH1A1DGKAFAAHHCAR2 | |
| SCHEMBL10027878 | 0.84 | MAPT (0.58) | MAPTALDH1A1FAAHCYP3A4USP2 | |
| SCHEMBL10027877 | 0.84 | DGKA (0.41) | MAPTALDH1A1DGKAFAAHCYP3A4 | |
| SCHEMBL21193802 | 0.84 | DGKA (0.41) | MAPTALDH1A1DGKAFAAHCYP3A4 | |
| SCHEMBL10027885 | 0.84 | MAPT (0.58) | MAPTALDH1A1FAAHCYP3A4USP2 | |
| SCHEMBL27909318 | 0.83 | DGKA (0.61) | DGKAFAAHFFAR1FFAR4LMNA | |
| SCHEMBL6930109 | 0.83 | MAPT (0.54) | MAPTALDH1A1DGKAFAAHCYP3A4 | |
| SCHEMBL28675407 | 0.83 | MAPT (0.60) | MAPTALDH1A1FAAHCYP3A4HCAR2 | |
| SCHEMBL30968801 | 0.83 | MAPT (0.60) | MAPTALDH1A1FAAHCYP3A4HCAR2 | |
| SCHEMBL27925927 | 0.80 | MAPT (0.66) | MAPTALDH1A1FAAHCYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119839-B2 | Carboxylic acid and antidepressant composition containing the same as active ingredient | YAMADA APICULTURE CENTER, INC. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119839-B2 | Carboxylic acid and antidepressant composition containing the same as active ingredient | YAMADA APICULTURE CENTER, INC. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100184860-A1 | Novel Carboxylic Acid and Antidepressant Composition Containing the Same as Active Ingredient | YAMADA APICULTURE CENTER, INC. (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20100184860-A1 | Novel Carboxylic Acid and Antidepressant Composition Containing the Same as Active Ingredient | YAMADA APICULTURE CENTER, INC. (JP) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184860-A1 | Novel Carboxylic Acid and Antidepressant Composition Containing the Same as Active Ingredient | HSD17B11, HCAR2, HSD11B1 | MAPT 2782/4885ALDH1A1 109/4885DGKA 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.