Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.30 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.30 |
| ▸ | MVD | P53602 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666575 | 0.94 | LPAR3 (0.42) | LPAR3LPAR2CHRM2CHRM1CHRM3 | |
| SCHEMBL27256342 | 0.82 | LPAR3 (0.42) | LPAR3LPAR2CHRM2CHRM1CHRM3 | |
| SCHEMBL337522 | 0.80 | MEN1 (0.34) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL28992249 | 0.78 | CHRM2 (0.34) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL27692513 | 0.76 | MVD (0.36) | LPAR3LPAR2CHRM2CHRM1CHRM3 | |
| SCHEMBL27727865 | 0.76 | MVD (0.36) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL28992248 | 0.74 | MEN1 (0.36) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL3988371 | 0.72 | MEN1 (0.34) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL4454861 | 0.72 | MEN1 (0.34) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL27457178 | 0.70 | MVD (0.33) | CHRM2CHRM1CHRM3MVD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195578-B | Use of phosphorothioate derivatives as skin depigmenting agents | 塞恩提斯有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-109195578-B | Use of phosphorothioate derivatives as skin depigmenting agents | 塞恩提斯有限公司 | 2021-12-24 | — | — | CN | disclosed |