Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749544 | 0.84 | KMT2A (0.47) | KDM4EL3MBTL1HTTGAAKMT2A | |
| SCHEMBL19774580 | 0.76 | KDM4E (0.67) | KDM4EL3MBTL1TYK2HTTNT5E | |
| SCHEMBL20176980 | 0.74 | KDM4E (0.55) | KDM4EL3MBTL1TYK2HTTNT5E | |
| SCHEMBL31171356 | 0.69 | TYK2 (0.58) | KDM4EL3MBTL1TYK2HTTROCK2 | |
| SCHEMBL15006463 | 0.68 | POLB (0.40) | HTTKMT2A | |
| Methyl Alcohol SCHEMBL28281305 | 0.68 | GAA (0.84) | KDM4EL3MBTL1TYK2HTTNT5E | |
| SCHEMBL13947140 | 0.67 | KDM4E (0.81) | KDM4EL3MBTL1TYK2HTTNT5E | |
| SCHEMBL14716526 | 0.67 | KDM4E (1.00) | KDM4EL3MBTL1TYK2HTTNT5E | |
| SCHEMBL1898755 | 0.67 | GAA (0.91) | KDM4EL3MBTL1TYK2HTTNT5E | |
| Water SCHEMBL11515613 | 0.67 | TSHR (0.67) | KDM4EL3MBTL1TYK2HTTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874375-A | Cyclic amide compounds and methods thereof for the treatment of rabies | 株式会社大分大学先端医学研究所 | 2021-12-31 | — | — | CN | disclosed |