Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316758 | 0.82 | NR5A1 (0.47) | NR5A1TSHRTHRATHRBPLA2G4B | |
| SCHEMBL3312285 | 0.82 | NR5A1 (0.47) | NR5A1TSHRPLA2G4BPLA2G2ATP53 | |
| SCHEMBL2873250 | 0.80 | NR5A1 (0.53) | NR5A1TSHRPLA2G4BTP53LTA4H | |
| SCHEMBL92107 | 0.76 | LTA4H (0.41) | NR5A1TSHRLTA4H | |
| SCHEMBL2871871 | 0.73 | NR5A1 (0.59) | NR5A1TSHRPLA2G4BTP53LTA4H | |
| SCHEMBL347683 | 0.71 | NR5A1 (0.62) | NR5A1TSHRTHRAPLA2G4BTP53 | |
| SCHEMBL4945033 | 0.71 | NR5A1 (0.62) | NR5A1TSHRTHRAPLA2G4BTP53 | |
| SCHEMBL10642885 | 0.71 | NR5A1 (0.62) | NR5A1TSHRTHRAPLA2G4BTP53 | |
| Hydrochloric Acid SCHEMBL7572318 | 0.71 | NR5A1 (0.58) | NR5A1TSHRPLA2G4BTP53LTA4H | |
| SCHEMBL11095674 | 0.71 | NR5A1 (0.79) | NR5A1TSHRPLA2G4BTP53LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120231037-A1 | CRYSTALLINE DRUG-CONTAINING COATINGS | Yissum Research Development Companyof the Hebrew U (IL) | 2012-09-13 | — | — | US | disclosed |
| WO-2010086863-A2 | CRYSTALLINE DRUG-CONTAINING COATINGS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-08-05 | — | — | WO | disclosed |