Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660356 | 0.83 | PRKDC (0.34) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28655766 | 0.77 | PIK3CA (0.35) | PIK3CAPIK3CDPIK3CBPIK3CGLRRK2 | |
| SCHEMBL30853317 | 0.68 | FGFR4 (0.44) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL27186898 | 0.68 | CNR2 (0.36) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL14374406 | 0.68 | PRKDC (0.39) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30030718 | 0.58 | PRKDC (0.57) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL6844511 | 0.58 | PRKDC (0.57) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL13545318 | 0.58 | PRKDC (0.33) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30031644 | 0.58 | PRKDC (0.48) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL17623866 | 0.57 | PDPK1 (0.38) | PIK3CAPIK3CDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727758-A | Bicyclic heterocyclic compounds and use thereof | 锐新医药公司 | 2021-11-30 | — | — | CN | disclosed |