Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 4/20 | 0.44 |
| ▸ | PRKDC | P78527 | 7/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071549 | 0.76 | FGFR4 (0.49) | FGFR4 | |
| SCHEMBL30529792 | 0.76 | PIK3CA (0.39) | PRKDCJAK2PIK3CAPIK3CDPIK3CG | |
| SCHEMBL19508034 | 0.75 | FGFR4 (0.40) | FGFR4 | |
| SCHEMBL27186898 | 0.75 | CNR2 (0.36) | PRKDCPIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL14374406 | 0.73 | PRKDC (0.39) | PRKDCPIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL6621275 | 0.72 | FGFR4 (0.48) | FGFR4PRKDCPIK3CA | |
| SCHEMBL6620594 | 0.72 | FGFR4 (0.52) | FGFR4JAK2 | |
| SCHEMBL17396389 | 0.71 | PRKDC (0.41) | PRKDCJAK2PIK3CAPIK3CDPIK3CG | |
| SCHEMBL6621209 | 0.71 | FGFR4 (0.49) | FGFR4JAK2 | |
| SCHEMBL28660356 | 0.70 | PRKDC (0.34) | FGFR4PRKDCJAK2PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |