Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.39 |
| ▸ | DCUN1D2 | Q6PH85 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351292 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL717218 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL21723001 | 0.87 | CYP2A6 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL16756188 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL28740601 | 0.79 | CYP2A6 (0.48) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL18921876 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL12831587 | 0.75 | ADORA1 (0.45) | ALDH1A1HSD17B10HPGD | |
| Benzene SCHEMBL28035419 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL21447 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL2361430 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113956278-B | Synthesis method of 5, 5-spirosilafluorene through C-H arylation cyclization reaction | 中钢集团南京新材料研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-113956278-A | Synthesis method of 5, 5-spirosilafluorene through C-H arylation cyclization reaction | 中钢集团南京新材料研究院有限公司 | 2022-01-21 | — | — | CN | disclosed |