Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.47 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926788 | 0.86 | MAT2A (0.58) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL28675693 | 0.83 | MAT2A (0.49) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL31361390 | 0.81 | MAT2A (0.48) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL31361461 | 0.80 | MAT2A (0.51) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL31361358 | 0.80 | MAT2A (0.47) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL28678700 | 0.80 | SMN1; SMN2 (0.52) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL31361434 | 0.80 | MAT2A (0.51) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL31361363 | 0.80 | MAT2A (0.49) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL19972089 | 0.79 | MAT2A (0.52) | MAT2ASLC11A2MAPTTP53HPGD | |
| SCHEMBL28677799 | 0.79 | MAT2A (0.48) | MAT2ASLC11A2MAPTTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-113999232-A | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2022-02-01 | — | — | CN | disclosed |