Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.48 |
| ▸ | JAK1 | P23458 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 8/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676987 | 0.99 | CDK4 (0.54) | CDK4HDAC6HDAC1JAK1BRD4 | |
| SCHEMBL28695669 | 0.86 | HDAC1 (0.59) | HDAC6HDAC1JAK1BRD4JAK2 | |
| SCHEMBL28673278 | 0.85 | HDAC1 (0.60) | HDAC6HDAC1JAK1BRD4JAK2 | |
| Ammonia Solution, Strong SCHEMBL29005328 | 0.81 | CDK4 (0.49) | CDK4HDAC6JAK1AURKAJAK2 | |
| SCHEMBL30445681 | 0.81 | CDK4 (0.49) | CDK4HDAC6JAK1AURKAJAK2 | |
| Ammonia Solution, Strong SCHEMBL29005335 | 0.80 | CDK4 (0.50) | CDK4HDAC6JAK1AURKAJAK2 | |
| SCHEMBL30445224 | 0.80 | CDK4 (0.50) | CDK4HDAC6JAK1AURKAJAK2 | |
| SCHEMBL28690412 | 0.79 | CDK2 (0.56) | CDK4HDAC6AURKAAURKBCDK2 | |
| SCHEMBL29368259 | 0.79 | CDK2 (0.56) | CDK4HDAC6AURKAAURKBCDK2 | |
| SCHEMBL29005369 | 0.77 | CDK2 (0.49) | CDK4HDAC1JAK1JAK2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999210-A | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2022-02-01 | — | — | CN | claimed |
| CN-113999210-A | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2022-02-01 | — | — | CN | disclosed |