SCHEMBL2867673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2872522	0.78	AURKA (0.62)	TTKAURKAMAP2K4ITKLRRK2
	SCHEMBL13198198	0.76	AURKA (0.57)	TTKAURKAITKLRRK2
	SCHEMBL12281691	0.75	TTK (0.69)	TTKAURKAPLK4CHEK2CYP3A4
	SCHEMBL2582318	0.74	TTK (0.68)	TTKAURKAPLK4CHEK2CYP3A4
	SCHEMBL12281934	0.74	TTK (0.70)	TTKAURKAPLK4CHEK2CYP3A4
	SCHEMBL2871104	0.74	TTK (0.48)	TTKAURKAMAP2K4ITKMAPK8
	SCHEMBL2868589	0.71	MAP2K4 (0.69)	TTKAURKAMAP2K4ITKMAPK8
	SCHEMBL5374305	0.71	MAP2K4 (0.46)	TTKAURKAMAP2K4AURKBMAPK8
	SCHEMBL2866811	0.71	MAP2K4 (0.55)	TTKAURKAMAP2K4LRRK2MAPK8
	SCHEMBL2865036	0.71	PDPK1 (0.65)	TTKAURKAITKMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.