SCHEMBL2865036

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5381639	0.89	AAK1 (0.59)	PDPK1ULK1ITKCSNK2A1AAK1
	SCHEMBL2871320	0.86	PDPK1 (0.66)	PDPK1ULK1ITKCSNK2A1
	SCHEMBL5381303	0.85	AAK1 (0.52)	PDPK1ULK1ITKCSNK2A1AAK1
	SCHEMBL6545151	0.84	TTK (0.49)	PDPK1ULK1ITKCSNK2A1AAK1
	SCHEMBL8251891	0.84	ULK1 (0.61)	PDPK1ULK1ITK
	SCHEMBL10214710	0.84	MAPKAPK2 (0.58)	PDPK1ULK1ITK
	SCHEMBL8254064	0.84	ULK1 (0.59)	PDPK1ULK1ITKCSNK2A1AAK1
	SCHEMBL5377953	0.81	CLK2 (0.53)	PDPK1ITKCSNK2A1AAK1TTK
	SCHEMBL2867415	0.81	ULK1 (0.64)	PDPK1ULK1ITK
	SCHEMBL13198185	0.81	PDPK1 (0.52)	PDPK1ULK1ITKCSNK2A1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.