Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334315 | 0.78 | DHODH (0.68) | MAPTLMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7331517 | 0.78 | DHODH (0.68) | MAPTLMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL31520498 | 0.78 | HTT (0.70) | RXFP1MAPTALDH1A1HPGDHTT | |
| SCHEMBL5180736 | 0.78 | HTT (0.70) | RXFP1MAPTALDH1A1HPGDHTT | |
| SCHEMBL29763550 | 0.77 | GRM1 (0.52) | RXFP1GRM4CHEK1AURKADAPK3 | |
| SCHEMBL4255638 | 0.76 | DHODH (0.73) | MAPTLMNAALDH1A1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL5180774 | 0.76 | HTT (0.68) | RXFP1MAPTALDH1A1HPGDHTT | |
| SCHEMBL14924421 | 0.75 | RXFP1 (0.63) | RXFP1LMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL8719654 | 0.75 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL22405623 | 0.75 | LCK (0.47) | RXFP1HPGDPOLBCHEK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613722-A | Novel imidazole-pyrazole derivatives | 豪夫迈·罗氏有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-113613722-A | Novel imidazole-pyrazole derivatives | 豪夫迈·罗氏有限公司 | 2021-11-05 | — | — | CN | disclosed |