Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290973 | 0.88 | KCNA5 (0.47) | NQO2IDO1HPGDPOLBKCNA5 | |
| SCHEMBL6094751 | 0.83 | NQO2 (0.55) | NQO2IDO1KCNA5TSHRLMNA | |
| SCHEMBL6682212 | 0.81 | NQO2 (0.53) | NQO2IDO1POLBTSHRLMNA | |
| SCHEMBL30408678 | 0.81 | NQO2 (0.53) | NQO2IDO1POLBTSHRLMNA | |
| SCHEMBL6674376 | 0.80 | NQO2 (0.52) | NQO2IDO1HPGDPOLBTSHR | |
| SCHEMBL24492288 | 0.79 | NQO2 (0.51) | NQO2IDO1POLBTSHRLMNA | |
| SCHEMBL29649218 | 0.79 | NQO2 (0.51) | NQO2IDO1POLBTSHRLMNA | |
| SCHEMBL26977894 | 0.77 | NQO2 (0.52) | NQO2IDO1HPGDPOLBKCNA5 | |
| SCHEMBL4521175 | 0.76 | TSHR (0.50) | NQO2TSHRLMNAMAPTNPC1 | |
| SCHEMBL375762 | 0.76 | MEN1 (0.48) | NQO2IDO1KCNA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117723694-A | Method for detecting C3 content of candesartan cilexetil intermediate in candesartan cilexetil | 河南省药品医疗器械检验院(河南省疫苗批签中心) | 2024-03-19 | — | — | CN | claimed |
| CN-117705981-A | Method for rapidly determining impurity content of candesartan cilexetil tablet intermediate | 河南省药品医疗器械检验院(河南省疫苗批签中心) | 2024-03-15 | — | — | CN | claimed |
| CN-114163391-B | Candesartan intermediate and preparation method of Candesartan | 迪嘉药业集团股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114163391-A | Candesartan intermediate and preparation method of candesartan | 迪嘉药业集团有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-117723694-A | Method for detecting C3 content of candesartan cilexetil intermediate in candesartan cilexetil | 河南省药品医疗器械检验院(河南省疫苗批签中心) | 2024-03-19 | — | — | CN | disclosed |
| CN-117723694-A | Method for detecting C3 content of candesartan cilexetil intermediate in candesartan cilexetil | 河南省药品医疗器械检验院(河南省疫苗批签中心) | 2024-03-19 | — | — | CN | disclosed |
| CN-114163391-B | Candesartan intermediate and preparation method of Candesartan | 迪嘉药业集团股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-113544113-B | Synthesis method of candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-113929597-A | Method for synthesizing candesartan cilexetil intermediate | 临海市华南化工有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-111909136-A | Preparation method of candesartan cilexetil | 珠海润都制药股份有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-101646659-A | Preparation method of candesartan cilexetil and intermediate thereof | SHANGHAI TOPHARMAN CO LTD | 2010-02-10 | — | — | CN | disclosed |