Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375762 | 0.92 | MEN1 (0.48) | NQO2IDO1KCNA5FOLH1MEN1 | |
| SCHEMBL29347085 | 0.89 | TDP1 (0.51) | NQO2KCNA5MEN1KMT2ASIGMAR1 | |
| SCHEMBL20777755 | 0.89 | NQO2 (0.55) | NQO2IDO1KCNA5MEN1KMT2A | |
| SCHEMBL166559 | 0.87 | LMNA (0.55) | NQO2IDO1KCNA5MEN1KMT2A | |
| SCHEMBL24086511 | 0.86 | NQO2 (0.53) | NQO2IDO1KCNA5MEN1KMT2A | |
| SCHEMBL1808874 | 0.85 | KCNA5 (0.56) | NQO2IDO1KCNA5FOLH1MEN1 | |
| SCHEMBL26659635 | 0.84 | KCNA5 (0.55) | NQO2IDO1KCNA5FOLH1MEN1 | |
| SCHEMBL5467303 | 0.84 | NQO2 (0.54) | NQO2IDO1KCNA5MEN1KMT2A | |
| SCHEMBL26673855 | 0.84 | IDO1 (0.50) | NQO2IDO1KCNA5LMNAMALT1 | |
| SCHEMBL28677441 | 0.83 | NQO2 (0.51) | NQO2IDO1KCNA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069711-A1 | FAP-TARGETED NEUTRON CAPTURE AGENTS, AND USES AND FORMULATIONS RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | CTXT PTY LIMITED (AU) | 2021-12-09 | — | — | US | disclosed |
| CN-111909044-A | Synthesis method of 2- (alkylamino) ethyl benzoate compound | 南京爱德程医药科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-7053122-B2 | Therapeutic use of aryl amino acid derivatives | PFIZER INC (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040138197-A1 | Therapeutic use of aryl amino acid derivatives | MAW GRAHAM NIGEL (GB) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | KAT5, KAT6A, KAT2A | NQO2 3187/4885IDO1 1960/4885KCNA5 650/4885 |
| US-20040138197-A1 | Therapeutic use of aryl amino acid derivatives | CNR1, HCRTR1, HTR6 | NQO2 3479/4885IDO1 1265/4885KCNA5 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.