SCHEMBL2867812

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862134	0.87	CSNK1D (0.54)	MAPK1TTKMAPK3CSNK1D
	SCHEMBL2870086	0.86	KDM4E (0.54)	MAPK1TTKMAPK3CSNK1DROCK2
	SCHEMBL2861653	0.82	MAPK1 (0.74)	MAPK1TTKMAPK3CSNK1DAURKB
	SCHEMBL2862933	0.79	MAPK1 (0.56)	MAPK1TTKMAPK3CSNK1DAURKB
	SCHEMBL27536329	0.79	MAPK1 (0.56)	MAPK1TTKMAPK3CSNK1DAURKB
	SCHEMBL2858476	0.78	MAP2K4 (0.68)	MAPK1TTKMAPK3
	SCHEMBL2868599	0.78	MAP2K4 (0.57)	MAPK1TTKMAPK3CSNK1DAURKB
	SCHEMBL28745171	0.77	MAPK1 (0.50)	MAPK1TTKMAPK3CSNK1D
	SCHEMBL2867928	0.77	HPGD (0.62)	MAPK1TTKMAPK3CSNK1DNPC1
	SCHEMBL2872493	0.77	MAPK1 (0.57)	MAPK1TTKMAPK3CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.