SCHEMBL28678136

SCHEMBL28678136

Cc1ccccc1OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.64
RXRB P28702 1/20 0.64
RXRG P48443 1/20 0.64
MAPT P10636 4/20 0.53
KMT2A Q03164 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
SLC6A3 Q01959 1/20 0.51
POLB P06746 1/20 0.51
LPAR1 Q92633 2/20 0.51
LPAR5 Q9H1C0 2/20 0.51
MEN1 O00255 2/20 0.50
PPARG P37231 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
JAK2 O60674 1/20 0.46
USP2 O75604 1/20 0.46
GAA P10253 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28678134 0.93 POLB (0.57) RXRARXRBRXRGMAPTKMT2A
SCHEMBL1284160 0.91 KMT2A (0.63) RXRARXRBRXRGMAPTKMT2A
SCHEMBL11584715 0.88 MAPT (0.58) RXRARXRBRXRGMAPTKMT2A
SCHEMBL13554415 0.87 ESR1 (0.59) MAPTKMT2ASMN1; SMN2POLBTDP1
SCHEMBL10782892 0.87 MAPT (0.62) RXRARXRBRXRGMAPTKMT2A
SCHEMBL2831997 0.86 KMT2A (0.54) RXRARXRBRXRGMAPTKMT2A
SCHEMBL1129956 0.86 RXRA (0.51) RXRARXRBRXRGMAPTKMT2A
Trimethylammonium SCHEMBL6221456 0.86 KMT2A (0.58) RXRARXRBRXRGMAPTKMT2A
SCHEMBL8387767 0.84 KMT2A (0.59) RXRARXRBRXRGMAPTKMT2A
SCHEMBL11761673 0.83 KMT2A (0.50) RXRARXRBRXRGMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072454-A Metal-organic structure having terephthalic acid-based ligand 学校法人立教学院 2022-02-18 CN disclosed