Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | RHEB | Q15382 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27908792 | 0.85 | HTR1B (0.46) | HTR1BRHEBHTR1ADRD4DRD3 | |
| Ethoxycarbonyl Group SCHEMBL27891885 | 0.84 | HTR1B (0.51) | HTR1BHTR1ADRD4DRD3DRD2 | |
| SCHEMBL29992707 | 0.83 | RHEB (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29445066 | 0.83 | RHEB (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL321761 | 0.83 | RHEB (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ethoxycarbonyl Group SCHEMBL27369293 | 0.82 | AHR (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ethoxycarbonyl Group SCHEMBL27472078 | 0.82 | DRD4 (0.53) | HTR1BHTR1ADRD4DRD3DRD2 | |
| Ethoxycarbonyl Group SCHEMBL27965810 | 0.81 | PARP1 (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ethoxycarbonyl Group SCHEMBL27906753 | 0.81 | TRPA1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Ethoxycarbonyl Group SCHEMBL27524232 | 0.81 | RHEB (0.46) | HTR1BRHEBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-B | Synthetic method of 2-substituted indole derivative | 中国医学科学院药物研究所 | 2021-12-07 | — | — | CN | disclosed |