Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 5/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 8/20 | 0.48 |
| ▸ | JAK1 | P23458 | 3/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13504386 | 0.82 | NUDT1 (0.62) | NUDT1EGLN2JAK1JAK3HSP90AB1 | |
| SCHEMBL18366694 | 0.78 | NUDT1 (0.61) | NUDT1EGLN2JAK1JAK3HSP90AB1 | |
| SCHEMBL2250300 | 0.74 | NUDT1 (0.73) | NUDT1EGLN2JAK1JAK3JAK2 | |
| SCHEMBL3099050 | 0.73 | NUDT1 (0.58) | NUDT1EGLN2JAK1JAK3JAK2 | |
| SCHEMBL3215698 | 0.73 | NUDT1 (0.67) | NUDT1EGLN2JAK1JAK3JAK2 | |
| SCHEMBL12518501 | 0.72 | NUDT1 (0.58) | NUDT1EGLN2JAK1JAK3 | |
| SCHEMBL27038245 | 0.72 | NUDT1 (0.56) | NUDT1EGLN2JAK1JAK3HSP90AB1 | |
| SCHEMBL3087585 | 0.72 | NUDT1 (0.69) | NUDT1EGLN2JAK1JAK3JAK2 | |
| SCHEMBL2144054 | 0.71 | NUDT1 (1.00) | NUDT1EGLN2JAK1JAK3JAK2 | |
| SCHEMBL31507670 | 0.70 | NUDT1 (0.39) | NUDT1EGLN2JAK1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922437-B | Bridged piperidine derivatives | 豪夫迈·罗氏有限公司 | 2021-12-10 | — | — | CN | disclosed |