SCHEMBL28678348

SCHEMBL28678348

CC[C@@H](N)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28388293 1.00 CA2 (0.31) CA2
SCHEMBL15610456 0.79
SCHEMBL19616288 0.79 MAPK1 (0.31)
SCHEMBL26947095 0.75
SCHEMBL15034581 0.74 TSHR (0.30)
SCHEMBL6309278 0.73
SCHEMBL17354689 0.73
SCHEMBL28530995 0.73
SCHEMBL2849077 0.73
SCHEMBL17375326 0.73 CA2 (0.32) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113825757-B Substituted fused bicyclic derivatives, preparation method thereof and application thereof in medicine 江苏恒瑞医药股份有限公司 2023-10-20 CN disclosed
CN-113825757-A Substituted condensed bicyclic derivatives, preparation method and application thereof in medicines 江苏恒瑞医药股份有限公司 2021-12-21 CN disclosed