SCHEMBL28678386

SCHEMBL28678386

CCn1ccc2c3c(N)nc(N)nc3ccc21

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 9/20 0.73
F2R P25116 6/20 0.72
DHFR P00374 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24164685 0.84 F2R (1.00) SLC2A1F2RDHFR
SCHEMBL4757057 0.83 SLC2A1 (1.00) SLC2A1F2RDHFR
SCHEMBL30252213 0.83 SLC2A1 (1.00) SLC2A1F2RDHFR
SCHEMBL11614190 0.82 SLC2A1 (0.77) SLC2A1F2RDHFR
SCHEMBL16210655 0.81 F2R (0.81) SLC2A1F2RDHFR
SCHEMBL28676490 0.81 SLC2A1 (0.64) SLC2A1F2RDHFR
SCHEMBL11614277 0.81 SLC2A1 (1.00) SLC2A1F2RDHFR
SCHEMBL31061154 0.80 DHFR (1.00) SLC2A1F2RDHFR
SCHEMBL11612134 0.80 DHFR (1.00) SLC2A1F2RDHFR
SCHEMBL23027766 0.80 F2R (0.80) SLC2A1F2RDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107536835-B Application of 1, 3-diamino-7H-pyrrole [3,2-f ] quinazoline derivative as antibacterial drug and drug 宁夏医科大学 2021-07-30 CN disclosed