SCHEMBL28678584

SCHEMBL28678584

Cc1cc(C)cc(-c2c(C)ccc3c2C=C(c2ccc(C)o2)C3[Zr])c1

nearest known ligand 0.31

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499685 0.91 KDM4E (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL22499655 0.87 PTGS1 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL28688102 0.86 CHRM2 (0.30) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL22499755 0.85
SCHEMBL2235084 0.85 MAPT (0.39) SLC9A1KDM4EMEN1ALDH1A1MAPT
SCHEMBL22499757 0.85 PTGS1 (0.39) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL2234850 0.85 KDM4E (0.31) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL22499698 0.85 KDM4E (0.34) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL28661546 0.85 ALDH1A1 (0.36) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL22499689 0.83 ALDH1A1 (0.34) ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631591-A Method for producing catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer 日本聚丙烯株式会社 2021-11-09 CN disclosed