Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ATXN2 | Q99700 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18860226 | 1.00 | ENPP2 (0.47) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL18838494 | 1.00 | ENPP2 (0.47) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL31546588 | 0.93 | HDAC1 (0.43) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL18860325 | 0.93 | HDAC1 (0.43) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL31546586 | 0.93 | HDAC1 (0.43) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL28679692 | 0.93 | HDAC1 (0.43) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL18838340 | 0.90 | SMN1; SMN2 (0.51) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL18838495 | 0.89 | ENPP2 (0.44) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL18838370 | 0.84 | NAMPT (0.47) | ENPP2HDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL18838396 | 0.83 | KCNH2 (0.48) | HDAC1CYP2C19MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3340988-B1 | ION CHANNEL INHIBITORY COMPOUNDS, PHARMACEUTICAL FORMULATIONS AND USES | AFASCI INC (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-108289886-B | Ion channel inhibiting compounds, pharmaceutical formulations and uses | 安华赛公司 | 2022-01-28 | — | — | CN | disclosed |