Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21881956 | 0.79 | TSHR (0.45) | BRD4NOS3NOS1NOS2 | |
| SCHEMBL21881994 | 0.79 | TSHR (0.45) | BRD4NOS3NOS1NOS2 | |
| SCHEMBL10491077 | 0.78 | MAPT (0.49) | BRD4LMNA | |
| Brivaracetam SCHEMBL2408675 | 0.77 | CA1 (0.49) | BRD4NOS3NOS1NOS2LMNA | |
| Brivaracetam SCHEMBL563380 | 0.77 | CA1 (0.49) | BRD4NOS3NOS1NOS2LMNA | |
| Brivaracetam SCHEMBL122081 | 0.77 | CA1 (0.49) | BRD4NOS3NOS1NOS2LMNA | |
| Brivaracetam SCHEMBL22446812 | 0.77 | CA1 (0.49) | BRD4NOS3NOS1NOS2LMNA | |
| Brivaracetam SCHEMBL564055 | 0.77 | CA1 (0.49) | BRD4NOS3NOS1NOS2LMNA | |
| Brivaracetam SCHEMBL563970 | 0.77 | CA1 (0.49) | BRD4NOS3NOS1NOS2LMNA | |
| Brivaracetam SCHEMBL563666 | 0.77 | CA1 (0.49) | BRD4NOS3NOS1NOS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113908153-A | Buvalracetam pharmaceutical composition, preparation method and application thereof | 上海博志研新药物技术有限公司 | 2022-01-11 | — | — | CN | disclosed |