Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125635 | 0.76 | CYP2C19 (0.51) | CYP2C19CYP2D6PKMSMN1; SMN2SLC6A3 | |
| SCHEMBL1458053 | 0.76 | CYP2C19 (0.51) | CYP2C19CYP2D6PKMSMN1; SMN2SLC6A3 | |
| SCHEMBL1458049 | 0.76 | CYP2C19 (0.51) | CYP2C19CYP2D6PKMSMN1; SMN2SLC6A3 | |
| SCHEMBL10584727 | 0.73 | EPHX1 (0.54) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL11032151 | 0.72 | CYP2C19 (0.56) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| Lithium Ion SCHEMBL1457968 | 0.72 | CYP2C19 (0.44) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| Lithium Ion SCHEMBL1458160 | 0.72 | CYP2C19 (0.44) | CYP2C19CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL1758751 | 0.71 | CYP2C19 (0.40) | CYP2C19CYP2D6CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL5955000 | 0.69 | TSHR (0.31) | TSHR | |
| SCHEMBL2886387 | 0.69 | CYP2C19 (0.43) | CYP2C19CYP2D6CYP3A4HCAR2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174281-A | Degradation agent for cyclin dependent kinase 7(CDK7) and use thereof | 达纳-法伯癌症研究公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113993519-A | Degradation agent for cyclin dependent kinase 12(CDK12) and use thereof | 达纳-法伯癌症研究公司 | 2022-01-28 | — | — | CN | disclosed |