Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697650 | 0.88 | ADORA2A (0.45) | KDM4EADORA2AADORA1SMN1; SMN2LMNA | |
| SCHEMBL29350070 | 0.88 | ADORA2A (0.45) | KDM4EADORA2AADORA1SMN1; SMN2LMNA | |
| SCHEMBL3651608 | 0.80 | MAPT (0.42) | KDM4EPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7617663 | 0.80 | ALDH1A1 (0.41) | KDM4EPKMADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL28679026 | 0.77 | ADORA2A (0.37) | KDM4EADORA2AADORA1SMN1; SMN2LMNA | |
| SCHEMBL580412 | 0.76 | TDP1 (0.32) | TDP1 | |
| SCHEMBL28671930 | 0.73 | CLK4 (0.50) | KDM4EADORA2AADORA1SMN1; SMN2LMNA | |
| SCHEMBL11145941 | 0.73 | KDM4E (0.48) | KDM4EPKMADORA2ASMN1; SMN2LMNA | |
| SCHEMBL28697652 | 0.72 | ADORA2A (0.43) | KDM4EADORA2AADORA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9138181 | 0.71 | KDM4E (0.47) | KDM4EPKMADORA2AADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113956295-B | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-113956295-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-01-21 | — | — | CN | disclosed |