Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751045 | 1.00 | SLC7A5 (0.57) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL5297391 | 0.85 | SLC7A5 (0.62) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL29478421 | 0.85 | SLC7A5 (0.62) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL43915 | 0.85 | SLC7A5 (0.62) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL289165 | 0.85 | SLC7A5 (0.62) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL43914 | 0.85 | SLC7A5 (0.62) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL29397861 | 0.85 | SLC7A5 (0.62) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL2497331 | 0.82 | SLC7A5 (0.73) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL455225 | 0.82 | SLC7A5 (0.73) | SLC7A5PTGS1ALOX15HIF1AKDM4E | |
| SCHEMBL29393527 | 0.82 | SLC7A5 (0.73) | SLC7A5PTGS1ALOX15HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057714-B | Heterocyclyl-substituted aminotriazole derivatives and their use | 苏州健雄职业技术学院 | 2023-07-14 | — | — | CN | disclosed |
| CN-114057714-A | Heterocyclyl-substituted aminotriazole derivatives and their use | 苏州健雄职业技术学院 | 2022-02-18 | — | — | CN | disclosed |