Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 11/20 | 0.68 |
| ▸ | BTK | Q06187 | 4/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.42 |
| ▸ | SRC | P12931 | 7/20 | 0.42 |
| ▸ | LYN | P07948 | 4/20 | 0.42 |
| ▸ | FLT1 | P17948 | 3/20 | 0.42 |
| ▸ | FLT4 | P35916 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365983 | 1.00 | FGFR4 (0.68) | FGFR4BTKFGFR1FGFR2FGFR3 | |
| SCHEMBL28699499 | 0.93 | FGFR4 (0.60) | FGFR4BTKFGFR1FGFR2FGFR3 | |
| SCHEMBL30365563 | 0.93 | FGFR4 (0.63) | FGFR4BTKFGFR1FGFR2FGFR3 | |
| SCHEMBL28683029 | 0.93 | FGFR4 (0.63) | FGFR4BTKFGFR1FGFR2FGFR3 | |
| SCHEMBL30365649 | 0.93 | FGFR4 (0.60) | FGFR4BTKFGFR1FGFR2FGFR3 | |
| SCHEMBL30365929 | 0.85 | FGFR4 (0.70) | FGFR4BTKFGFR1FGFR2FGFR3 | |
| SCHEMBL25162437 | 0.83 | FGFR4 (0.72) | FGFR4BTKFGFR1FGFR2FGFR3 | |
| SCHEMBL28932257 | 0.80 | FGFR4 (0.71) | FGFR4FGFR1FGFR2FGFR3SRC | |
| SCHEMBL30365611 | 0.80 | FGFR4 (0.71) | FGFR4FGFR1FGFR2FGFR3SRC | |
| SCHEMBL30365318 | 0.80 | FGFR4 (0.79) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912602-B | 2-oxo-1, 2-dihydro-1, 6-naphthyridine-7-yl compound and preparation method and application thereof | 温州医科大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-113912602-A | 2-oxo-1, 2-dihydro-1, 6-naphthyridine-7-based compound and preparation method and application thereof | 温州医科大学 | 2022-01-11 | — | — | CN | disclosed |