Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457622 | 0.84 | GAA (0.64) | GAAPKMLMNAHTTNOX1 | |
| SCHEMBL469849 | 0.84 | NOX1 (0.84) | GAAPKMLMNAHTTNOX1 | |
| SCHEMBL10836155 | 0.83 | GAA (1.00) | GAAPKMLMNAHTTNOX1 | |
| SCHEMBL29191732 | 0.83 | MEN1 (0.60) | GAAPKMLMNAHTTMEN1 | |
| SCHEMBL19277757 | 0.83 | KMT2A (0.74) | GAALMNANOX1MEN1KMT2A | |
| SCHEMBL469851 | 0.81 | NOX1 (0.73) | GAALMNANOX1MEN1KMT2A | |
| SCHEMBL2095091 | 0.80 | SMN1; SMN2 (0.67) | LMNAHTTMEN1KMT2APOLB | |
| SCHEMBL28641155 | 0.79 | NOX1 (0.66) | GAAPKMLMNAHTTNOX1 | |
| SCHEMBL10099725 | 0.75 | GAA (0.83) | GAALMNAHTTNOX1MEN1 | |
| SCHEMBL5636116 | 0.75 | MAOB (0.66) | GAALMNAHTTNOX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970668-B | Method for preparing 3-thio-1, 2, 4-triazole compound | 普济生物科技（台州）有限公司 | 2021-12-07 | — | — | CN | disclosed |