Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28693080 | 0.90 | STAT3 (0.64) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28693620 | 0.90 | STAT3 (0.52) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28699093 | 0.90 | CTDSP1 (0.62) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28683191 | 0.89 | MEN1 (0.54) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28681436 | 0.88 | STAT3 (0.61) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28672562 | 0.85 | CHEK1 (0.60) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28695985 | 0.85 | STAT3 (0.55) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28673399 | 0.84 | MEN1 (0.58) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28683183 | 0.84 | CHEK1 (0.58) | ALDH1A1KDM4EL3MBTL1POLBMEN1 | |
| SCHEMBL28699068 | 0.84 | STAT3 (0.54) | ALDH1A1KDM4EL3MBTL1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |