Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616893 | 0.79 | GAA (0.37) | GAAHPGDSALKBH2ALDH1A1NPC1 | |
| SCHEMBL221485 | 0.77 | GAA (0.59) | GAAHPGDSALKBH2MAPTNPC1 | |
| SCHEMBL1569965 | 0.77 | EPHX2 (0.47) | GAAHPGDSALKBH2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL18397939 | 0.76 | GAA (0.57) | GAAHPGDSALKBH2MAPTNPC1 | |
| SCHEMBL28592022 | 0.76 | RAB9A (0.37) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2121774 | 0.71 | CYP2A6 (0.53) | GAAL3MBTL1 | |
| SCHEMBL6733486 | 0.71 | GAA (0.41) | GAAHPGDSALKBH2ALDH1A1MAPT | |
| SCHEMBL160432 | 0.69 | NOTUM (0.48) | GAAALDH1A1MAPTNPC1 | |
| SCHEMBL29431733 | 0.69 | EPHX2 (0.49) | GAAHPGDSALKBH2ALDH1A1MAPT | |
| SCHEMBL27638750 | 0.69 | NPC1 (0.50) | MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710664-A | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2021-11-26 | — | — | CN | disclosed |