Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12497077 | 0.85 | ALDH1A1 (0.50) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL15986613 | 0.81 | GAA (0.65) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL9631014 | 0.80 | ALDH1A1 (0.69) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL14428159 | 0.80 | ALK (0.51) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL29267932 | 0.80 | ALDH1A1 (0.69) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL14315671 | 0.79 | ALDH1A1 (0.67) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL15968528 | 0.78 | GAA (1.00) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL25129316 | 0.77 | ALDH1A1 (0.64) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL15791720 | 0.77 | GAA (0.65) | HTTALDH1A1GAATDP1ALOX15 | |
| SCHEMBL17863893 | 0.77 | GAA (0.59) | HTTALDH1A1GAATDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912621-A | Containing SO2Spiro pyrrolocarbazoles and application thereof | 北京云基科技有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-113861217-A | Containing SO2Polyheterocyclic compounds and uses thereof | 北京云基科技有限公司 | 2021-12-31 | — | — | CN | disclosed |