Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 8/20 | 0.45 |
| ▸ | TYK2 | P29597 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21222934 | 0.84 | GAA (0.46) | HPGDGSK3BRAB9AHTT | |
| SCHEMBL14818761 | 0.81 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL18640737 | 0.79 | DHODH (0.54) | HPGDGSK3BJAK2TYK2LMNA | |
| SCHEMBL31139248 | 0.78 | JAK2 (0.49) | HPGDGSK3BJAK2TYK2LMNA | |
| SCHEMBL15104669 | 0.78 | RAB9A (0.46) | LMNASMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL27833750 | 0.77 | GSK3B (0.49) | HPGDGSK3BGSK3AKMT2A | |
| SCHEMBL14803573 | 0.77 | TRPV1 (0.46) | HPGDGSK3BJAK2TYK2LMNA | |
| SCHEMBL374899 | 0.76 | KMT2A (0.46) | SMN1; SMN2NPC1RAB9AMEN1HTT | |
| SCHEMBL6902503 | 0.76 | MAPT (0.42) | HPGDLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL25241815 | 0.76 | TYK2 (0.50) | HPGDGSK3BJAK2TYK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767101-A | Novel indole-2-carboxamides having anti-Hepatitis B Virus (HBV) activity | 艾库里斯有限及两合公司 | 2021-12-07 | — | — | CN | disclosed |