Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762706 | 0.84 | THRB (0.42) | THRBHRH3MAPK1BTKDDB1 | |
| SCHEMBL28294668 | 0.80 | HRH3 (0.40) | THRBHRH3MAPK1BTKDDB1 | |
| SCHEMBL9954696 | 0.79 | HRH3 (0.42) | THRBHRH3MAPK1BTKDDB1 | |
| SCHEMBL12401941 | 0.79 | HRH3 (0.42) | THRBHRH3MAPK1BTKDDB1 | |
| SCHEMBL15167444 | 0.75 | MAPK1 (0.40) | HRH3MAPK1BTKHPGD | |
| SCHEMBL1139839 | 0.74 | MAPK1 (0.40) | THRBHRH3MAPK1BTKDDB1 | |
| SCHEMBL10058228 | 0.74 | MAPK1 (0.40) | THRBHRH3MAPK1BTKDDB1 | |
| SCHEMBL20743818 | 0.74 | HRH3 (0.43) | HRH3MAPK1BTKHPGD | |
| SCHEMBL1700349 | 0.72 | HRH3 (0.44) | HRH3MAPK1BTKDDB1CRBN | |
| SCHEMBL1690233 | 0.71 | HRH3 (0.49) | HRH3MAPK1BTKHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874079-A | Bridged tricyclic carbamoylpyridone compounds and pharmaceutical use thereof | 吉利德科学公司 | 2021-12-31 | — | — | CN | disclosed |