Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20681620 | 1.00 | ACE (0.40) | ACERENKDM4EF2LMNA | |
| SCHEMBL28619551 | 1.00 | ACE (0.40) | ACERENKDM4EF2LMNA | |
| SCHEMBL10166855 | 1.00 | ACE (0.40) | ACERENKDM4EF2LMNA | |
| SCHEMBL10167020 | 0.91 | BIRC2 (0.37) | F2BIRC2XIAPBIRC3 | |
| SCHEMBL28604275 | 0.91 | PEPD (0.39) | F2LMNAPEPDBIRC2XIAP | |
| SCHEMBL25092400 | 0.91 | PEPD (0.39) | F2LMNAPEPDBIRC2XIAP | |
| SCHEMBL10166931 | 0.90 | BIRC2 (0.42) | F2BIRC2XIAPBIRC3 | |
| SCHEMBL28370502 | 0.90 | ACE (0.38) | ACERENKDM4EF2LMNA | |
| SCHEMBL28370504 | 0.90 | ACE (0.38) | ACERENKDM4EF2LMNA | |
| SCHEMBL1163393 | 0.86 | XIAP (0.49) | BIRC2XIAPBIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677399-A | Bivalent antagonists of inhibitor of apoptosis proteins | 和博医药有限公司 | 2021-11-19 | — | — | CN | disclosed |