Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665720 | 0.90 | MAPT (0.54) | MAPTGAATHRBTP53ALDH1A1 | |
| SCHEMBL28667773 | 0.88 | MAPT (0.62) | MAPTGAATHRBTP53ALDH1A1 | |
| SCHEMBL28667847 | 0.88 | MAPT (0.56) | MAPTGAATHRBTP53ALDH1A1 | |
| SCHEMBL28930626 | 0.88 | MAPT (0.68) | MAPTGAATHRBTP53HTR1A | |
| SCHEMBL28688168 | 0.88 | MAPT (0.53) | MAPTGAATHRBTP53SLC6A2 | |
| SCHEMBL28676593 | 0.85 | MAPT (0.53) | MAPTGAATHRBTP53ALDH1A1 | |
| SCHEMBL28661668 | 0.83 | MAPT (0.51) | MAPTGAATHRBTP53ALDH1A1 | |
| SCHEMBL28665641 | 0.83 | MAPT (0.58) | MAPTGAATHRBTP53HTR1A | |
| SCHEMBL28665638 | 0.83 | MAPT (0.48) | MAPTGAATHRBTP53HTR1A | |
| SCHEMBL28665714 | 0.82 | MAPT (0.64) | MAPTGAATHRBTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658889-B | 1,2, 4-oxadiazole-aryl piperazine compound containing naphthalene ring and preparation method and application thereof | 贵州医科大学 | 2021-12-17 | — | — | CN | disclosed |