Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28703838 | 0.79 | PDE3B (0.43) | PDE3BPDE3ANOTUMMAOBMAOA | |
| SCHEMBL8828114 | 0.71 | — | — | |
| SCHEMBL28932271 | 0.70 | NPC1 (0.50) | PDE3BPDE3APOLBNOTUMMAOB | |
| SCHEMBL28677904 | 0.69 | PDE3B (0.51) | PDE3BPDE3ANOTUMCA1CA2 | |
| SCHEMBL339071 | 0.67 | POLB (0.38) | POLBNOTUMCRBN | |
| SCHEMBL20702890 | 0.64 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL28683146 | 0.64 | RPS6KB2 (0.38) | PDE3BPDE3APOLBMAOB | |
| SCHEMBL5565984 | 0.64 | AXL (0.58) | PDE3BPDE3APOLBNOTUMCRBN | |
| SCHEMBL2644564 | 0.64 | MEN1 (0.50) | MAOBMAOA | |
| SCHEMBL11627707 | 0.63 | SMN1; SMN2 (0.59) | PDE3BPDE3ANOTUMCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999131-B | Method for preparing amide derivative by amination of alkyl C-H bond under catalysis of nickel promoted by visible light | 苏州大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113999131-A | Method for preparing amide derivative by amination of alkyl C-H bond under catalysis of nickel promoted by visible light | 苏州大学 | 2022-02-01 | — | — | CN | disclosed |