Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31553378 | 0.75 | PDE3B (0.44) | ALDH1A1SMN1; SMN2PBRM1PDE3BPDE3A | |
| SCHEMBL8082831 | 0.71 | KDM4E (0.44) | RPS6KB2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8828114 | 0.71 | — | — | |
| SCHEMBL7765362 | 0.69 | MAPT (0.56) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL4731535 | 0.69 | ALDH1A1 (0.37) | RPS6KB2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL11710676 | 0.68 | NOTUM (0.46) | RPS6KB2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL22246046 | 0.66 | KMT2A (0.44) | RPS6KB2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL20522794 | 0.64 | AXL (0.53) | KDM4EMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL22246023 | 0.64 | PRKDC (0.35) | RPS6KB2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1549500 | 0.64 | MEN1 (0.50) | KDM4EMEN1MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999131-B | Method for preparing amide derivative by amination of alkyl C-H bond under catalysis of nickel promoted by visible light | 苏州大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113999131-A | Method for preparing amide derivative by amination of alkyl C-H bond under catalysis of nickel promoted by visible light | 苏州大学 | 2022-02-01 | — | — | CN | disclosed |