Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.67 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683182 | 1.00 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28683173 | 0.94 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28677883 | 0.94 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28677884 | 0.94 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28699554 | 0.92 | ADIPOR2 (0.68) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28683176 | 0.92 | ADIPOR2 (0.68) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28683178 | 0.92 | ADIPOR2 (0.68) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28699551 | 0.92 | ADIPOR2 (0.68) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28932258 | 0.91 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 | |
| SCHEMBL28683100 | 0.91 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1POLBUSP2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107686463-B | Chalcone aryloxy acetamide compound, preparation method and application thereof | 安徽中医药大学 | 2022-02-01 | — | — | CN | disclosed |