ADIPOR2

Adiponectin receptor protein 2 · Q86V24 · ADIPOR2 on Sugi Atlas →

427 patent compounds predicted against ADIPOR2, 361 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL17938602 SCHEMBL17938602 1.00 1/20
SCHEMBL17950883 SCHEMBL17950883 0.90 1/20
SCHEMBL17946118 SCHEMBL17946118 0.88 1/20
SCHEMBL24514564 SCHEMBL24514564 0.82 1/20
SCHEMBL24514572 SCHEMBL24514572 0.81 1/20
SCHEMBL17946047 SCHEMBL17946047 0.80 1/20
SCHEMBL24514563 SCHEMBL24514563 0.80 1/20
SCHEMBL21064273 SCHEMBL21064273 0.78 1/20
SCHEMBL17945987 SCHEMBL17945987 0.78 1/20
SCHEMBL25568932 SCHEMBL25568932 0.77 1/20
SCHEMBL20662532 SCHEMBL20662532 0.77 1/20
SCHEMBL28677883 SCHEMBL28677883 0.73 1/20
SCHEMBL28677884 SCHEMBL28677884 0.73 1/20
SCHEMBL28683173 SCHEMBL28683173 0.73 1/20
SCHEMBL24514196 SCHEMBL24514196 0.73 1/20
SCHEMBL25568933 SCHEMBL25568933 0.73 1/20
SCHEMBL24514569 SCHEMBL24514569 0.70 1/20
SCHEMBL5129236 SCHEMBL5129236 0.70 1/20
SCHEMBL17946000 SCHEMBL17946000 0.70 1/20
SCHEMBL24514573 SCHEMBL24514573 0.69 1/20

Clinical trials — most relevant to ADIPOR2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of n-3 Fatty Acid Supplementation on Serum Levels, and Gene Expression of type2 Diabetes Patient PHASE4UNKNOWN
Effect Of Exenatide Treatment on Liver Fat Content in Patients With Diabetes PHASE4COMPLETED
The Impact of Omega-3 Supplementation on Gene Expression in Type 2 Diabetics PHASE4UNKNOWN
Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes PHASE3COMPLETED
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction PHASE2RECRUITING
Adiponectin Polymorphisms, Insulin Resistance, and Pharmacokinetics in Obesity PHASE1COMPLETED
Insulin Regulation of Lipolysis and Lipolysis Proteins EARLY_PHASE1RECRUITING
Study of Menstrual Irregularities and Endometrial Pathology in Women Undergoing Bariatric Surgery nanCOMPLETED
Increased Expression of Adiponectin Receptor 2 in the Mononuclear Cells in Children With Prader-Willi Syndrome nanCOMPLETED
Normal Serum Adiponectin Levels in Females nanUNKNOWN
Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study nanCOMPLETED
Group Lifestyle Intervention for People With New Onset Type 2 Diabetes. nanCOMPLETED
Study of the Relationship Between Serum Adiponectin and Clinical Prognosis in Patients Undergoing Cardiac Surgery nanUNKNOWN
HMB for Denutrition in Patients With Cirrhosis (HEPATIC) nanCOMPLETED
BATokines as Biomarkers of Brown Fat in Humans nanACTIVE_NOT_RECRUITING
High Intensity Interval Training in Pre and Postmenopausal Women With Type II Diabetes. nanCOMPLETED
The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients nanUNKNOWN
Serum Adiponectin in Chinese Population and Its Correlation to Cardiovascular and Cerebrovascular Diseases nanRECRUITING
Calorie Restriction in Multiple Sclerosis nanACTIVE_NOT_RECRUITING
Effect of Angiotensin Receptor Blockade on Insulin Resistance and Adipose Tissue Cytokines in Type 2 Diabetes nanCOMPLETED
Paediatric Obesity and Cardiovascular Dysfunction nanCOMPLETED
Age, Lifestyle, Muscle Mechanisms in Insulin Resistance nanCOMPLETED
Plasma Adiponectin Concentration, Activity and Isoforms in Newly Diagnosed and Untreated Type 2 Diabetes Mellitus nanUNKNOWN
Leptin Biology in Adipose Tissue nanCOMPLETED
Chemerin, Fetuin-A, IL-34 and IL-13 Levels in Diabetic Periodontitis Patients nanCOMPLETED
Body Composition Estimated by Bioelectrical Impedance Analysis in Patients with Acute Coronary Syndrome. nanRECRUITING
Pentoxifylline Versus Pioglitazone In Non-Alcoholic Steatohepatiti (NASH) nanUNKNOWN
Precision Exercise in Obese Children With Bronchial Asthma nanCOMPLETED
Depletion of Liver Fat in Type 2 Diabetes nanRECRUITING
Effect of Alcohol on Cephalic Phase Reflex and Gene Expression nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ADIPOR2 binder may also engage these)

ProteinNameSimilarity
Q91VH1 1.000 Q91VH1 →
ADIPOR1 Adiponectin receptor protein 1 0.997 landscape →
Q8BQS5 0.996 Q8BQS5 →
Q94177 0.992 Q94177 →
Q9VCY8 0.992 Q9VCY8 →
Q753H5 0.986 Q753H5 →
Q09910 0.984 Q09910 →
Q09749 0.982 Q09749 →
Q12442 0.981 Q12442 →
Q03419 0.981 Q03419 →
Q9ZUH8 0.980 Q9ZUH8 →
Q02896 0.980 Q02896 →
Q60WT2 0.980 Q60WT2 →
A8WZU4 0.980 A8WZU4 →
O45145 0.980 O45145 →
P25625 0.979 P25625 →
Q61086 0.978 Q61086 →
Q84N34 0.977 Q84N34 →
O60353 0.977 O60353 →
Q9P6N9 0.977 Q9P6N9 →
Q6TMJ1 0.977 Q6TMJ1 →
Q0WMJ8 0.976 Q0WMJ8 →
Q55DQ0 0.976 Q55DQ0 →
Q8WMU5 0.976 Q8WMU5 →
Q500Z2 0.976 Q500Z2 →
Q93VV0 0.976 Q93VV0 →
Q95ZE3 0.976 Q95ZE3 →
Q8IUH5 0.976 Q8IUH5 →
Q5RCN4 0.976 Q5RCN4 →
Q7K0P4 0.975 Q7K0P4 →