Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429090 | 1.00 | HTR6 (0.49) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL29429027 | 1.00 | HTR6 (0.49) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL29429076 | 0.92 | HTR6 (0.43) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL28696215 | 0.92 | HTR6 (0.43) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL29429052 | 0.92 | HTR6 (0.43) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL29429045 | 0.92 | KMT2A (0.44) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL29429023 | 0.92 | KMT2A (0.44) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL29429103 | 0.92 | HTR6 (0.43) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL28690221 | 0.92 | KMT2A (0.44) | HTR6KMT2AL3MBTL1HAO1APP | |
| SCHEMBL29429049 | 0.92 | HTR6 (0.43) | HTR6KMT2AL3MBTL1HAO1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | claimed |
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |