Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991302 | 0.77 | TDP1 (0.53) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL16844598 | 0.75 | ALDH1A1 (0.43) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL29959394 | 0.75 | TDP1 (0.50) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6139432 | 0.75 | TDP1 (0.50) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL11494592 | 0.73 | ALDH1A1 (0.44) | TDP1KMT2ASLC6A2ALDH1A1L3MBTL1 | |
| SCHEMBL29388715 | 0.73 | ALDH1A1 (0.89) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL50441 | 0.73 | ALDH1A1 (0.89) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6402746 | 0.72 | TDP1 (0.59) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL24117922 | 0.72 | TDP1 (0.54) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2588443 | 0.71 | ALDH1A1 (0.72) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874079-A | Bridged tricyclic carbamoylpyridone compounds and pharmaceutical use thereof | 吉利德科学公司 | 2021-12-31 | — | — | CN | disclosed |