SCHEMBL28685174

SCHEMBL28685174

CCCCC(CC)COc1ccccc1C(=O)OCC

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
CYP3A4 P08684 3/20 0.69
CA2 P00918 1/20 0.69
LMNA P02545 3/20 0.63
PRSS1 P07477 1/20 0.62
PRSS2 P07478 1/20 0.62
PRSS3 P35030 1/20 0.62
TSHR P16473 7/20 0.52
MAPK1 P28482 4/20 0.52
HSD17B10 Q99714 3/20 0.46
KDM4E B2RXH2 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TBXAS1 P24557 1/20 0.45
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5918234 0.94 ALDH1A1 (0.80) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL28685170 0.89 ALDH1A1 (0.62) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL6402307 0.87 ALDH1A1 (0.91) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL30343699 0.85 ALDH1A1 (0.62) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL31750409 0.85 ALDH1A1 (0.62) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL28295778 0.85 ALDH1A1 (0.62) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL128501 0.85 ALDH1A1 (0.62) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL31751235 0.85 ALDH1A1 (0.62) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL4167259 0.85 PRSS1 (0.74) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL308555 0.85 PRSS1 (0.60) ALDH1A1CYP3A4CA2LMNAPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114008119-A Glycol ether aryl ester plasticizers 伊士曼化工公司 2022-02-01 CN claimed
CN-114008119-A Glycol ether aryl ester plasticizers 伊士曼化工公司 2022-02-01 CN disclosed