Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685390 | 1.00 | MET (0.40) | METPDGFRBPDGFRAKDR | |
| SCHEMBL31037116 | 1.00 | MET (0.40) | METPDGFRBPDGFRAKDR | |
| SCHEMBL28685388 | 1.00 | MET (0.40) | METPDGFRBPDGFRAKDR | |
| SCHEMBL30239150 | 0.79 | MET (0.48) | MET | |
| SCHEMBL30239263 | 0.76 | ADORA2A (0.39) | — | |
| SCHEMBL28457671 | 0.76 | ADORA2A (0.39) | — | |
| SCHEMBL28457670 | 0.76 | ADORA2A (0.39) | — | |
| SCHEMBL28457672 | 0.76 | ADORA2A (0.39) | — | |
| SCHEMBL20238259 | 0.75 | — | — | |
| SCHEMBL12165434 | 0.75 | MET (0.49) | METPDGFRBPDGFRAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861199-A | Imidazo [4,5-b ] pyrazine compound, preparation method and application thereof | 上海医药集团股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113861200-A | Imidazo [4,5-b ] pyrazine compound, preparation method and application thereof | 上海医药集团股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113861198-A | Imidazo [4,5-b ] pyrazine compound, preparation method and application thereof | 上海医药集团股份有限公司 | 2021-12-31 | — | — | CN | disclosed |