Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13976998 | 0.92 | EGFR (0.46) | EGFRERBB2SRCPTGESALK | |
| SCHEMBL29775134 | 0.92 | EGFR (0.46) | EGFRERBB2SRCPTGESALK | |
| SCHEMBL529236 | 0.92 | SRC (0.44) | EGFRERBB2SRCMALT1PTGES | |
| SCHEMBL5256795 | 0.80 | PTGES (0.48) | EGFRERBB2SRCPTGESGAK | |
| SCHEMBL19877265 | 0.76 | SRC (0.47) | EGFRERBB2SRCLMNA | |
| SCHEMBL21143331 | 0.75 | TNF (0.48) | MALT1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24010609 | 0.74 | CHRM4 (0.45) | EGFRERBB2SRCTNFLMNA | |
| SCHEMBL2632169 | 0.74 | SRC (0.44) | EGFRERBB2SRCALDH1A1 | |
| SCHEMBL12928111 | 0.74 | SRC (0.38) | EGFRERBB2SRCALDH1A1 | |
| SCHEMBL27911201 | 0.74 | MAPT (0.43) | EGFRERBB2SRCCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993848-A | Inhibitors of PAPD5 and methods of use thereof | 儿童医学中心公司 | 2022-01-28 | — | — | CN | disclosed |