SCHEMBL28685683

SCHEMBL28685683

O=[N+]([O-])c1c(O)c([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1O.[PbH2]

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
GPR35 Q9HC97 4/20 0.43
GRIN2D O15399 7/20 0.40
GRIN3B O60391 7/20 0.40
GRIN1 Q05586 7/20 0.40
GRIN2A Q12879 7/20 0.40
GRIN2B Q13224 7/20 0.40
GRIN2C Q14957 7/20 0.40
GRIN3A Q8TCU5 7/20 0.40
ALDH1A1 P00352 2/20 0.39
S100A4 P26447 1/20 0.39
CDK2 P24941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28688867 0.97 TSHR (0.46) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL29105094 0.95 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL30589392 0.95 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
Ammonia Solution, Strong SCHEMBL30589376 0.95 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL30589375 0.95 TSHR (0.44) TSHRGPR35GRIN2DGRIN3BGRIN1
Hydroxyamine SCHEMBL30589377 0.93 TSHR (0.43) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL28666838 0.87 S100A4 (0.46) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL1502113 0.84 S100A4 (0.48) TSHRGPR35GRIN2DGRIN3BGRIN1
SCHEMBL20985115 0.84 S100A4 (0.48) TSHRGPR35GRIN2DGRIN3BGRIN1
Water SCHEMBL3516244 0.81 S100A4 (0.46) TSHRGPR35GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113264837-B Energetic ion salt of 3, 5-dihydroxy-2, 4, 6-trinitrobenzene derivative and preparation method thereof 信阳师范学院 2023-09-29 CN disclosed
CN-113264837-A Energetic ionic salt of 3, 5-dihydroxy-2, 4, 6-trinitrobenzene derivative and preparation method thereof 信阳师范学院 2021-08-17 CN disclosed