Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643977 | 1.00 | SIRT2 (0.40) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL4048725 | 0.91 | CYP1A2 (0.39) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL31475214 | 0.91 | CYP1A2 (0.39) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL21198132 | 0.87 | CYP1A2 (0.44) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL29672454 | 0.86 | MAPT (0.40) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL31482836 | 0.86 | CYP1A2 (0.39) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL27338781 | 0.86 | MAPT (0.40) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL16308649 | 0.86 | MAPT (0.40) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL5375050 | 0.86 | CYP1A2 (0.39) | SIRT2CYP1A2HPGDMAPTALDH1A1 | |
| SCHEMBL12821556 | 0.84 | CYP1A2 (0.38) | SIRT2CYP1A2HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-B | Indazole compound, pharmaceutical composition and application thereof | 暨南大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-114072387-A | Indazole compound and medicinal composition and application thereof | 暨南大学 | 2022-02-18 | — | — | CN | disclosed |