SCHEMBL28686148

SCHEMBL28686148

CCCCOc1ccc(OC[C@H]2CC[C@H](CCC)CC2)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.39
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
HTR2B P41595 2/20 0.36
PTGES O14684 2/20 0.36
ALOX5 P09917 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
PPARG P37231 2/20 0.35
PSEN1 P49768 1/20 0.35
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
GRM2 Q14416 1/20 0.34
FFAR4 Q5NUL3 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13417705 1.00 RIPK1 (0.39) RIPK1HTR2AHTR2CHTR2BPTGES
SCHEMBL9562596 0.96 RIPK1 (0.37) RIPK1HTR2AHTR2CHTR2BPTGES
SCHEMBL9562592 0.96 RIPK1 (0.37) RIPK1HTR2AHTR2CHTR2BPTGES
SCHEMBL15445816 0.96 RIPK1 (0.37) RIPK1HTR2AHTR2CHTR2BPTGES
SCHEMBL9562600 0.96 RIPK1 (0.37) RIPK1HTR2AHTR2CHTR2BPTGES
SCHEMBL28697245 0.96 RIPK1 (0.38) RIPK1HTR2AHTR2CHTR2BPPARG
SCHEMBL15445794 0.96 RIPK1 (0.38) RIPK1HTR2AHTR2CHTR2BPPARG
SCHEMBL15445809 0.94 RIPK1 (0.39) RIPK1HTR2AHTR2CHTR2BPTGES
SCHEMBL26770233 0.94 HTR2A (0.40) RIPK1HTR2AHTR2CHTR2BPTGES
SCHEMBL10430230 0.93 RIPK1 (0.35) RIPK1HTR2AHTR2CHTR2BPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113980686-B Preparation method of lateral o-difluorobenzene liquid crystal compound containing cyclohexyl 宁夏中星显示材料有限公司 2023-10-10 CN disclosed
CN-113980686-A Preparation method of cyclohexyl-containing lateral o-difluorobenzene liquid crystal compound 宁夏中星显示材料有限公司 2022-01-28 CN disclosed