Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697278 | 1.00 | NOTUM (0.55) | NOTUMTSHRPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29749785 | 0.92 | NOTUM (0.49) | NOTUMTSHRALDH1A1KMT2AIRAK4 | |
| SCHEMBL29627833 | 0.92 | NOTUM (0.49) | NOTUMTSHRALDH1A1KMT2AIRAK4 | |
| SCHEMBL29627850 | 0.91 | NOTUM (0.50) | NOTUMTSHRALDH1A1KMT2APTPN1 | |
| SCHEMBL28706635 | 0.91 | NOTUM (0.48) | NOTUMTSHRALDH1A1KMT2AIRAK4 | |
| SCHEMBL28686207 | 0.91 | NOTUM (0.48) | NOTUMTSHRALDH1A1KMT2AIRAK4 | |
| SCHEMBL28691758 | 0.90 | NOTUM (0.49) | NOTUMTSHRALDH1A1KMT2APTPN1 | |
| SCHEMBL29627823 | 0.88 | TSHR (0.49) | NOTUMTSHRALDH1A1 | |
| SCHEMBL28698733 | 0.87 | TSHR (0.47) | NOTUMTSHRALDH1A1 | |
| SCHEMBL29627843 | 0.82 | TSHR (0.49) | NOTUMTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072405-A | Heterocyclic monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2022-02-18 | — | — | CN | disclosed |